Induction of heart tumours in Wistar rats after a single application of ethylmethanesulphonate and dimethylnitrosamine.
作者： H. Haas , J. Hilfrich , U. Mohr
DOI: 10.1007/BF00305022
关键词: Single application 、 Hematology 、 Tumour incidence 、 Ventricle 、 Medicine 、 Internal medicine 、 After treatment 、 Carcinogen 、 Endocrinology 、 Heart tumours 、 Sarcoma 、 Pathology
摘要: After a single treatment of different doses ethylmethanesulphonate (EMS : 100, 200 or 300 mg/kg b.w.) dimethylnitrosoamine (DMN: 30 as well in groups treated with both carcinogens combination, neoplastic alterations the left coronary ventricle were identified. These tumours diagnosed either neurofibromata neurinomata varying degrees differentiation. In one animal polymorphic sarcoma without neurogenic structures was seen. The tumour incidence highest after mg EMS/kg b.w. (6 40 rats).
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