Immunoelectron-microscopical labelling of glycolipids in the envelope of a demyelinating brain-derived RNA virus (Semliki Forest) by anti-glycolipid sera☆

作者: N.R.S. Evans , H.E. Webb

DOI: 10.1016/0022-510X(86)90113-9

关键词: BiologySemliki Forest virusImmunoelectron microscopyVirologyAlphavirusGalactocerebrosideHost cell membraneRNA virusViral envelopeGlycolipid

摘要: Immunoelectron-microscopical techniques using gold-labelled antibodies were used to localize the glycolipids ganglioside, glucocerebroside and galactocerebroside, spike glycoprotein antigens, in envelope of RNA virus Semliki Forest which had replicated mouse brain cell cultures. The demonstration host membrane glycolipid antigens viruses is discussed relation possibility an autoimmune reaction central nervous system cells.

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