A statistical evaluation of baseline and follow-up carcinoembryonic antigen in patients with resectable colorectal carcinoma.

摘要: A long-term CEA follow-up was evaluated statistically for a series of 74 patients with primary colorectal carcinoma who underwent resections cure. Thirty-three recurrences and 29 deaths were reported among this population after median interval 55 months. Preoperative levels correlated the Dukes' classification. However, preoperative level adds significant information to classification in prediction recurrence. Postoperative assays taken later clinical evaluation process carry most prognostic subsequent Using matched-pairs techniques, authors noted that often rose anticipation recurrence, sometimes as early one year before The following four events evaluated: 1) three consecutive rising CEAs; 2) rises 5.0 ng/ml; 3) exceeds 4) ng/ml two times. examined characterized by false positive rates ranging from 17% 66% true 43% 56% From evaluations, further investigation appeared warranted when exceeded at but chances finding any recurrent disease near 50%. Among experiencing recurrences, although forewarned elevations, there no time likely have recurrence disease.