作者: Hemda Rosenblum , Yehuda Shoenfeld , Howard Amital
DOI: 10.1016/J.IDC.2011.07.012
关键词: Genetic predisposition 、 Medicine 、 Diagnosis of exclusion 、 Chronic fatigue syndrome 、 Disease 、 Vaccination 、 Pathogenesis 、 Etiology 、 Immunology 、 Autoimmunity 、 Microbiology (medical) 、 Infectious Diseases
摘要: Chronic fatigue syndrome (CFS) is characterized by unexplained that lasts for at least 6 months with a constellation of other symptoms. Most cases start suddenly, and are usually accompanied flu-like illness. It symptom-based diagnosis exclusion, the pathogenesis which unknown. Studies have examined hypothesized about possible biomedical epidemiologic characteristics disease, including genetic predisposition, infections, endocrine abnormalities, immune dysfunction psychological psychosocial factors. Recently, AISA (autoimmune/inflammatory induced adjuvants) was recognized, indicating contribution adjuvants vaccines to development autoimmunity.