Radiowave dielectric investigation of boron compounds distribution in cultured tumour cells: relevance to boron neutron capture therapy
作者： S. Capuani , T. Gili , C. Cametti , B. Maraviglia , M. Colasanti
DOI: 10.1016/S0009-2614(02)00806-0
关键词: Cellular level 、 Dielectric spectroscopy 、 Distribution (pharmacology) 、 Neutron capture 、 Radiochemistry 、 Boron 、 Biodistribution 、 Dielectric 、 Chemistry 、 Borocaptate sodium
摘要: Abstract The distribution of two main Boron neutron capture therapy (BNCT) agents, borocaptate sodium ( BSH ) and borono-phenylalanine BPA ), in C6 rat glioma cells has been investigated by means radiowave dielectric spectroscopy measurements. Significant differences between treated with the different boron carriers were found magnitude passive electrical cell parameters. This technique offers a new procedure for measurement compounds interactions biological environments at cellular level is suggested to have potentiality becoming an attractive tool biodistribution studies BNCT tissues.
harvard.edu
elsevier.com
sci-hub.se 参考文章(14)
G. P. South, R. J. Sheppard, Edward Hector Grant, Dielectric behaviour of biological molecules in solution Clarendon Press. ,(1978)
Dieter Walz, Hermann Berg, Giulio Milazzo, Bioelectrochemistry of Cells and Tissues ,(2011)
F. Bordi, C. Cametti, T. Gili, Reduction of the contribution of electrode polarization effects in the radiowave dielectric measurements of highly conductive biological cell suspensions Bioelectrochemistry. ,vol. 54, pp. 53- 61 ,(2001) , 10.1016/S1567-5394(01)00110-4
H. Looyenga, Dielectric constants of heterogeneous mixtures. Physica D: Nonlinear Phenomena. ,vol. 31, pp. 401- 406 ,(1965) , 10.1016/0031-8914(65)90045-5
S. Takashima, A. Casaleggio, F. Giuliano, M. Morando, P. Arrigo, S. Ridella, Study of Bound Water of Poly-Adenine Using High Frequency Dielectric Measurements Biophysical Journal. ,vol. 49, pp. 1003- 1008 ,(1986) , 10.1016/S0006-3495(86)83728-6
Jacek Capala, Michael S. Makar, Jeffrey A. Coderre, Accumulation of Boron in Malignant and Normal Cells Incubated In Vitro with Boronophenylalanine, Mercaptoborane or Boric Acid Radiation Research. ,vol. 146, pp. 554- 560 ,(1996) , 10.2307/3579556
Teruyoshi Kageji, Birte Otersen, Detlef Gabel, René Huiskamp, Yoshinobu Nakagawa, Keizo Matsumoto, Interaction of mercaptoundecahydrododecaborate (BSH) with phosphatidylcholine: relevance to boron neutron capture therapy Biochimica et Biophysica Acta. ,vol. 1391, pp. 377- 383 ,(1998) , 10.1016/S0005-2760(98)00018-6
K. Asami, T. Yonezawa, Dielectric behavior of wild-type yeast and vacuole-deficient mutant over a frequency range of 10 kHz to 10 GHz Biophysical Journal. ,vol. 71, pp. 2192- 2200 ,(1996) , 10.1016/S0006-3495(96)79420-1
Rolf F. Barfh, Albert H. Soloway, Ralph G. Fairchild, Robert M. Brugger, Boron neutron capture therapy for cancer. Realities and prospects. Cancer. ,vol. 70, pp. 2995- 3007 ,(1992) , 10.1002/1097-0142(19921215)70:12<2995::AID-CNCR2820701243>3.0.CO;2-#
Peng-Peng P. Zhu Tang, Martin P. Schweizer, Kenneth M. Bradshaw, William F. Bauer, 11B nuclear magnetic resonance studies of the interaction of borocaptate sodium with serum albumin. Biochemical Pharmacology. ,vol. 49, pp. 625- 632 ,(1995) , 10.1016/0006-2952(94)00529-U