Selective uptake of boronophenylalanine by glioma stem/progenitor cells
作者： Ting Sun , Youxin Zhou , Xueshun Xie , Guilin Chen , Bin Li
DOI: 10.1016/J.APRADISO.2012.04.005
关键词:
摘要: The success of boron neutron capture therapy (BNCT) depends on the amount in cells and tumor/blood tumor/(normal tissue) concentration ratios. For first time, measurements uptake both stem/progenitor differentiated glioma were performed along with biodistribution suitable animal models. In cells, selective accumulation boronophenylalanine (BPA) was lower, retention after BPA removal longer than vitro. However, not statistically significantly different mice xenografts.
elsevier.com
sci-hub.se 参考文章(52)
Du Zw, [Establishment of human malignant glioma cell line (SHG-44) and observation on its characteristics]. Chinese journal of oncology. ,vol. 6, pp. 241- 243 ,(1984)
Weilian Yang, Rolf F. Barth, Joan H. Rotaru, Melvin L. Moeschberger, Darrel D. Joel, Marta M. Nawrocky, Joseph H. Goodman, Enhanced survival of glioma bearing rats following boron neutron capture therapy with blood-brain barrier disruption and intracarotid injection of boronophenylalanine. Journal of Neuro-oncology. ,vol. 33, pp. 59- 70 ,(1997) , 10.1023/A:1005769214899
Pedro R Lowenstein, Kader Yagiz, Kurt M Kroeger, Marianela Candolfi, Hikmat Assi, A K M Ghulam Muhammad, Mia K Wibowo, Weidong Xiong, Gregory J Baker, Maria G Castro, Gene therapy and virotherapy: novel therapeutic approaches for brain tumors. Discovery Medicine. ,vol. 10, pp. 293- 304 ,(2010)
Darrel D. Joel, Jeffrey A. Coderre, Peggy L. Micca, Marta M. Nawrocky, Effect of dose and infusion time on the delivery of p-boronophenylalanine for neutron capture therapy. Journal of Neuro-oncology. ,vol. 41, pp. 213- 221 ,(1999) , 10.1007/978-1-4615-1285-1_151
Paola Porcari, Silvia Capuani, Emanuela D'Amore, Mario Lecce, Angela La Bella, Fabrizio Fasano, Renzo Campanella, Luisa Maria Migneco, Francesco Saverio Pastore, Bruno Maraviglia, In vivo (19)F MRI and (19)F MRS of (19)F-labelled boronophenylalanine-fructose complex on a C6 rat glioma model to optimize boron neutron capture therapy (BNCT). Physics in Medicine and Biology. ,vol. 53, pp. 6979- 6989 ,(2008) , 10.1088/0031-9155/53/23/021
W. Yang, R.F. Barth, G. Wu, W. Tjarks, P. Binns, K. Riley, Boron neutron capture therapy of EGFR or EGFRvIII positive gliomas using either boronated monoclonal antibodies or epidermal growth factor as molecular targeting agents. Applied Radiation and Isotopes. ,vol. 67, ,(2009) , 10.1016/J.APRADISO.2009.03.030
Qiang Huang, Quan-Bin Zhang, Jun Dong, Yin-Yan Wu, Yun-Tian Shen, Yao-Dong Zhao, Yu-De Zhu, Yi Diao, Ai-Dong Wang, Qing Lan, Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro BMC Cancer. ,vol. 8, pp. 304- 304 ,(2008) , 10.1186/1471-2407-8-304
Katrin Lamszus, Hauke S. Günther, Glioma stem cells as a target for treatment Targeted Oncology. ,vol. 5, pp. 211- 215 ,(2010) , 10.1007/S11523-010-0155-4
Rolf F Barth, John C Grecula, Weilan Yang, Joan H Rotaru, Marta Nawrocky, Nilendu Gupta, Brent J Albertson, Amy K Ferketich, Melvin L Moeschberger, Jeffrey A Coderre, Einar K Rofstad, Combination of boron neutron capture therapy and external beam radiotherapy for brain tumors International Journal of Radiation Oncology Biology Physics. ,vol. 58, pp. 267- 277 ,(2004) , 10.1016/S0360-3016(03)01613-4
Feng Jin, Chao Gao, Lei Zhao, Hao Zhang, Hai-Tao Wang, Tong Shao, Shu-Ling Zhang, Yu-Jia Wei, Xiao-Bing Jiang, Yin-Pu Zhou, Hong-Yang Zhao, Using CD133 positive U251 glioblastoma stem cells to establish nude mice model of transplanted tumor. Brain Research. ,vol. 1368, pp. 82- 90 ,(2011) , 10.1016/J.BRAINRES.2010.10.051