A simplified approach to hyperthermic intraoperative intraperitoneal chemotherapy (HIIC) using a self retaining retractor.
作者： Paul H. Sugarbaker , Andrew M. Averbach , Pierre Jacquet , Arvil D. Stephens , Oswald Anthony Stuart
DOI: 10.1007/978-1-4613-1247-5_26
关键词: Surgery 、 Peritoneal carcinomatosis 、 Peritoneal cavity 、 Intraperitoneal chemotherapy 、 Medicine 、 Peritoneum 、 Retractor 、 Anesthesia 、 Drug concentration 、 Chemotherapy 、 Carcinosis
摘要: There are both pharmacologic and practical reasons for recommending intraoperative intraperitoneal chemotherapy. From a point of view, direct installation selected drugs into the peritoneal cavity results in large increase amount chemotherapy that reaches abdominal pelvic surfaces. This advantage is result peritoneal-plasma barrier. Molecules hydrophyllic leave more slowly than they metabolized systemically. Three-fore, great concentration difference exists at all times between drug within plasma [1,2].
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