Breakthrough in cachexia treatment through a novel selective androgen receptor modulator

摘要: Cachexia, and particularly the loss of metabolically active lean tissue, leads to increased morbidity mortality in affected patients. An impairment strength functional status is usually associated with cachexia. A variety anabolic appetite-stimulating agents have been studied patients cachexia caused by various underlying diseases. Overall, these studies demonstrated that treatment can increase body weight and/or mass. However, therapies may severe side effects, when utilizing testosterone related steroids targeting androgen receptor. These effects include cardiovascular problems, prostate hyperplasia cancer men, as well virilization women.