Hormone treatment and muscle anabolism during aging: Androgens

摘要: Aging is associated with a gradual decline in circulating testosterone concentrations and decreased musculature men. While administration often considered when symptoms of hypogonadism are presented, the long-term effects androgen use on muscle physiology not yet fully understood. The definition men remains obscure but generally indicated by total less than threshold value 300-500 ng/dL. Androgen replacement therapy safe women low endogenous concentrations. development selective receptor modulators (SARMs) may provide additional options treatment while lowering potential side use. administration, either alone or combination other treatments, can be successful improving mass increasing protein anabolism reducing catabolism women. Further research necessary to optimize anabolic anticatabolic properties androgens for prevention loss