DOI: 10.1016/S0882-4010(03)00061-5
关键词: Granulomatous amoebic encephalitis 、 Pathogenesis 、 Acanthamoeba keratitis 、 Immunology 、 Contact lens 、 Acanthamoeba 、 Protozoa 、 Biology 、 Naegleria fowleri 、 Microbiology 、 Aids patients
摘要: Acanthamoeba are free-living, harmless organisms, however, given the opportunity and appropriate conditions, they can cause painful, sight-threatening as well fatal infections and, thus, considered opportunistic pathogens. have become increasingly important in past few years due to increasing populations of contact lens users AIDS patients. The mechanisms associated with pathogenesis tend be highly complex, depending on parasite, host environmental factors. Elucidation biochemical, cellular molecular basis diseases caused by may lead development therapeutic interventions.