Differentiation of a cell line of myeloid leukemia.

作者: Yasuo Ichikawa

DOI: 10.1002/JCP.1040740303

关键词: Clone (cell biology)ImmunologyMyeloblastMolecular biologyCellular differentiationCell cultureTissue cultureBiologyIn vitroMyeloid leukemiaCell

摘要: A cell line was established in vitro from a spontaneous myeloid leukemia of SL strain mice. This cytologically identified as myeloblast, and its normal differentiation appeared to be completely blocked mass culture. When the cells were seeded soft agar with conditioned medium cells, either macrophages or neutrophil granulocytes single clone. The rate formation colonies containing differentiated always increased an increase concentration medium. this not effective that inducing differentiation.

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