Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific.
作者： Cristian Koepfli , Andreea Waltmann , Maria Ome-Kaius , Leanne J Robinson , Ivo Mueller
DOI: 10.1093/OFID/OFY240
关键词: Veterinary medicine 、 Real-time polymerase chain reaction 、 Population 、 Plasmodium vivax 、 Plasmodium 、 Multiplicity of infection 、 Transmission (mechanics) 、 Genotyping 、 Plasmodium falciparum 、 Medicine
摘要: Across 8101 individuals in 46 villages, the proportion of Plasmodium spp. multiple clone infections (0%-53.8%) did not reflect prevalence by quantitative polymerase chain reaction (qPCR; 1.9%-38.4%), except for P. vivax Solomon Islands (P < .001). Thus this parameter was informative to identify transmission foci. In contrast, microscopy and qPCR correlated well.
oup.com
sci-hub.se 参考文章(15)
Lucy S. Tusting, Teun Bousema, David L. Smith, Chris Drakeley, Measuring changes in Plasmodium falciparum transmission: Precision, accuracy and costs of metrics Advances in Parasitology. ,vol. 84, pp. 151- 208 ,(2014) , 10.1016/B978-0-12-800099-1.00003-X
Andreea Waltmann, Andrew W. Darcy, Ivor Harris, Cristian Koepfli, John Lodo, Ventis Vahi, David Piziki, G. Dennis Shanks, Alyssa E. Barry, Maxine Whittaker, James W. Kazura, Ivo Mueller, High Rates of Asymptomatic, Sub-microscopic Plasmodium vivax Infection and Disappearing Plasmodium falciparum Malaria in an Area of Low Transmission in Solomon Islands PLOS Neglected Tropical Diseases. ,vol. 9, pp. e0003758- 18 ,(2015) , 10.1371/JOURNAL.PNTD.0003758
Leanne J. Robinson, Rahel Wampfler, Inoni Betuela, Stephan Karl, Michael T. White, Connie S. N. Li Wai Suen, Natalie E. Hofmann, Benson Kinboro, Andreea Waltmann, Jessica Brewster, Lina Lorry, Nandao Tarongka, Lornah Samol, Mariabeth Silkey, Quique Bassat, Peter M. Siba, Louis Schofield, Ingrid Felger, Ivo Mueller, Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children: a randomised placebo-controlled trial and mathematical model. PLOS Medicine. ,vol. 12, ,(2015) , 10.1371/JOURNAL.PMED.1001891
T Smith, JLK Hii, B Genton, I Müller, M Booth, N Gibson, A Narara, MP Alpers, None, Associations of peak shifts in age-prevalence for human malarias with bednet coverage Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 95, pp. 1- 6 ,(2001) , 10.1016/S0035-9203(01)90314-1
Charlie Jennison, Alicia Arnott, Natacha Tessier, Livingstone Tavul, Cristian Koepfli, Ingrid Felger, Peter M. Siba, John C. Reeder, Melanie Bahlo, Ivo Mueller, Alyssa E. Barry, Plasmodium vivax Populations Are More Genetically Diverse and Less Structured than Sympatric Plasmodium falciparum Populations PLOS Neglected Tropical Diseases. ,vol. 9, pp. 1- 20 ,(2015) , 10.1371/JOURNAL.PNTD.0003634
Victor A Mobegi, Kovana M Loua, Ambroise D Ahouidi, Judith Satoguina, Davis C Nwakanma, Alfred Amambua-Ngwa, David J Conway, None, Population genetic structure of Plasmodium falciparum across a region of diverse endemicity in West Africa Malaria Journal. ,vol. 11, pp. 223- 223 ,(2012) , 10.1186/1475-2875-11-223
Standwell C. Nkhoma, Shalini Nair, Salma Al‐Saai, Elizabeth Ashley, Rose McGready, Aung P. Phyo, François Nosten, Tim J. C. Anderson, Population genetic correlates of declining transmission in a human pathogen Molecular Ecology. ,vol. 22, pp. 273- 285 ,(2013) , 10.1111/MEC.12099
Teun Bousema, Gillian Stresman, Amrish Y Baidjoe, John Bradley, Philip Knight, William Stone, Victor Osoti, Euniah Makori, Chrispin Owaga, Wycliffe Odongo, Pauline China, Shehu Shagari, Ogobara K Doumbo, Robert W Sauerwein, Simon Kariuki, Chris Drakeley, Jennifer Stevenson, Jonathan Cox, None, The Impact of Hotspot-Targeted Interventions on Malaria Transmission in Rachuonyo South District in the Western Kenyan Highlands: A Cluster-Randomized Controlled Trial. PLOS Medicine. ,vol. 13, ,(2016) , 10.1371/JOURNAL.PMED.1001993
Stephan Karl, Michael T White, George J Milne, David Gurarie, Simon I Hay, Alyssa E Barry, Ingrid Felger, Ivo Mueller, None, Spatial Effects on the Multiplicity of Plasmodium falciparum Infections PLOS ONE. ,vol. 11, pp. e0164054- 20 ,(2016) , 10.1371/JOURNAL.PONE.0164054
Andreea Waltmann, Cristian Koepfli, Natacha Tessier, Stephan Karl, Abebe Fola, Andrew W Darcy, Lyndes Wini, G. L. Abby Harrison, Céline Barnadas, Charlie Jennison, Harin Karunajeewa, Sarah Boyd, Maxine Whittaker, James Kazura, Melanie Bahlo, Ivo Mueller, Alyssa E. Barry, Long-term sustained malaria control leads to inbreeding and fragmentation of Plasmodium vivax populations bioRxiv. pp. 100610- ,(2016) , 10.1101/100610