Localization of four polypeptide hormones in the saurian pancreas

作者: William B. Rhoten , Phillip H. Smith

DOI: 10.1002/AJA.1001510410

关键词: SomatostatinHormoneEnteroendocrine cellInternal medicineEndocrine systemBiologyEndocrinologyGlucagonPancreasPancreatic polypeptideIslet

摘要: Glucagon, insulin, somatostatin, and pancreatic polypeptide have been localized in the anolian pancreas using peroxidase-antiperoxidase immunocytochemistry. The most abundant endocrine cell type contains glucagon. Insulin-containing cells are next numerous. Somatostatin-immunoreactive tend to be at periphery of islet cords. Pancreatic polypeptide-containing a minor component scattered throughout exocrine occasionally within areas. No staining was observed after application antigastrin serum.

参考文章(18)
S L Erlandsen, O D Hegre, J A Parsons, R C McEvoy, R P Elde, Pancreatic islet cell hormones distribution of cell types in the islet and evidence for the presence of somatostatin and gastrin within the D cell. Journal of Histochemistry and Cytochemistry. ,vol. 24, pp. 883- 897 ,(1976) , 10.1177/24.7.60437
William B. Rhoten, Emiocytosis of B granules from saurian pancreatic islets perifused in vitro American Journal of Anatomy. ,vol. 138, pp. 481- 497 ,(1973) , 10.1002/AJA.1001380406
William B. Rhoten, The cellular response of saurian pancreatic islets to chronic insulin administration. General and Comparative Endocrinology. ,vol. 20, pp. 474- 489 ,(1973) , 10.1016/0016-6480(73)90079-8
Phillip H. Smith, Pancreatic islets of the coturnix quail. A light and electron microscopic study with special reference to the islet organ of the splenic lobe. Anatomical Record-advances in Integrative Anatomy and Evolutionary Biology. ,vol. 178, pp. 567- 585 ,(1974) , 10.1002/AR.1091780305
Phillip H. Smith, Frederick W. Merchant, David G. Johnson, Wilfred Y. Fujimoto, Robert H. Williams, Immunocytochemical localization of a gastric inhibitory polypeptide-like material within A-cells of the endocrine pancreas† American Journal of Anatomy. ,vol. 149, pp. 585- 590 ,(1977) , 10.1002/AJA.1001490410
L.-I. Larsson, F. Sundler, R. H�kanson, Immunohistochemical localization of human pancreatic polypeptide (HPP) to a population of islet cells Cell and Tissue Research. ,vol. 156, pp. 167- 171 ,(1975) , 10.1007/BF00221800
R. H. Unger, The Banting Memorial Lecture 1975: Diabetes and the Alpha Cell Diabetes. ,vol. 25, pp. 136- 151 ,(1976) , 10.2337/DIAB.25.2.136
ROBERT L. HAZELWOOD, The Avian Endocrine Pancreas Integrative and Comparative Biology. ,vol. 13, pp. 699- 709 ,(1973) , 10.1093/ICB/13.3.699
Dana E. Johnson, Judith L. Torrence, Robert P. Elde, G. Eric Bauer, Bryan D. Noe, Donald J. Fletcher, Immunohistochemical localization of somatostatin, insulin and glucagon in the principal islets of the anglerfish (Lophius americanus) and the channel catfish (Ictalurus punctata) American Journal of Anatomy. ,vol. 147, pp. 119- 124 ,(1976) , 10.1002/AJA.1001470112