Indole, azaindole and related heterocyclic amidopiperazine derivatives
作者： John A. Bender , Kap-Sun Yeung , Zhongxing Zhang , Owen B. Wallace , Tao Wang
DOI:
关键词: Bicyclic molecule 、 Stereochemistry 、 Human immunodeficiency virus (HIV) 、 Indole test 、 Chemistry 、 Ring (chemistry) 、 Alkoxy group 、 Group (periodic table) 、 Alkyl
摘要: The invention comprises substituted indole, azaindole and related heterocyclic amidopiperazine derivatives of general Formula I wherein: Q is —may represent a bond; A selected from the group consisting C 1-6 alkoxy, alkyl, 3-7 cycloalkyl, phenyl, heteroaryl; wherein said heteroaryl may be monocyclic or bicyclic comprised three to eleven atoms C, N, NR 9 , O, S, each ring phenyl optionally with one five same different substituents R 19 -R 23 ; T U 7 S; V C(H) k 1 O N(R 7′ ) k; W CR 3 10 X 4 Y 5 Z 6 0 1; m, n, p are independently 0, 2 provided that sum must equal 2; compositions thereof their use as antiviral agents, particularly for treating HIV infection.
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