Effect of Non-Steroidal Anti-Inflammatory Drugs on Bone Healing
作者： Jessica Cottrell , J. Patrick O’Connor
DOI: 10.3390/PH3051668
关键词: Bone regeneration 、 Bone healing 、 Non steroidal anti inflammatory 、 Bioinformatics 、 Dosing 、 Analgesic 、 Surgery 、 Nonsteroidal 、 Cyclooxygenase 、 Medicine 、 Inflammation
摘要: Nonspecific and COX-2 selective nonsteroidal anti-inflammatory drugs (NSAIDs) function by inhibiting the cyclooxygenase isoenzymes effectively reduce pain inflammation attributed to acute or chronic musculoskeletal pathologies. However, use of NSAIDs as an analgesic is thought negatively contribute bone healing. This review strived provide a thorough unbiased analysis current research conducted on animals humans regarding their effect Specifically, this discusses role animal models, dosing regiments, outcome parameters when examining discrepancies about NSAIDS effects regeneration. The in regeneration needs be better defined order further elucidate impact
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