Changes in Serum 25-Hydroxyvitamin D and Plasma Intact PTH Levels Following Treatment With Ergocalciferol in Patients With CKD

摘要: Background Vitamin D insufficiency and deficiency are very common in patients with chronic kidney disease (CKD). The effect of ergocalciferol administration on serum 25-hydroxyvitamin plasma intact parathyroid hormone (PTH) levels these is not known. Study Design Retrospective study. Setting & Participants Patients CKD stage 3 or 4 who had a level less than 30 ng/mL ( Outcome Measurements 25-Hydroxyvitamin PTH were measured at baseline follow-up. Results 66 met inclusion criteria. Average age was 70.4 ± 1.3 (SE) years (range, 40 to 88 years), 97% men. There 44 (66%) 22 (33%) 4. After median follow-up 6 months, there significant increase from 16.6 0.7 27.2 1.8 (41 2 68 nmol/L; P 12 nmol/L) associated likelihood greater 30% decrease (odds ratio, 4.5; 95% confidence interval, 1.5 15.1; Limitations This retrospective study mostly male patients. Conclusions show that has favorable if therapy results an levels; this more evident 3.