FDG-PET after radiotherapy is a good prognostic indicator of rectal cancer.

作者: Shinya Oku , Keiichi Nakagawa , Toshimitsu Momose , Yoshitaka Kumakura , Atsushi Abe

DOI: 10.1007/BF02990079

关键词: Incidence (epidemiology)CancerTherapeutic effectNuclear medicineColorectal cancerGuidelineMedicinePositron emission tomographyStandardized uptake valueRadiation therapy

摘要: In the management of rectal cancer after combined therapy radiation and surgical operation, evaluation prognosis is important. Although fluoro-18-deoxy glucose positron emission tomography (FDG-PET) considered as a useful tool for therapeutic effect this well other cancers, however, there are few articles that clearly describe appropriate procedure FDG-PET in order to obtain best prognostic value. The purpose present study compare several variations semi-quantification method, Standardized Uptake Values (SUV) determine most parameter prediction propose quantitative guideline FDG-PET. Especially, authors focused on SUV radiotherapy, which had not been key value, it was rather taken mere indicator (radiotherapeutic) effect, direct itself.Methods: Forty patients with lower region underwent two series before pre-operative radiotherapy. Their SUVs were calculated from data compared results long-term follow-up histopathological outcomes.Results: All 40 high FDG uptake mean value radiotherapy (SUV1) 7.6. After (SUV2) decreased 4.2. There significant difference SUV2 between groups without recurrence (p<0.05), SUV1 or ratio (SUV2/SUV1) displayed no incidence recurrence.Conclusion: be good patients. nor SUV2/SUV1 did have equivalent usefulness. Subsets greater than 3.2 should observed closely.

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