Acceleration of Granulocytic Cell Recovery in Irradiated Mice by a Single Subcutaneous Injection of a Heat-Killed Lactobacillus casei Preparation
作者： MASAKO FURUSE , KAZUKO TSUNEOKA , KAZUMI UCHIDA , KOJI NOMOTO
DOI: 10.1269/JRR.38.111
关键词: Lymphopoiesis 、 Granulocyte 、 Lactobacillus casei 、 Spleen 、 Chemistry 、 Bone marrow 、 Lymphocyte 、 Microbiology 、 Molecular biology 、 Population 、 Granulopoiesis
摘要: Flow cytometric analysis showed that the treatment of irradiated mice with a heat-killed Lactobacillus casei preparation (LC 9018) accelerated recovery granulocytic cell populations in peripheral blood, spleen and femur bone marrow. The lymphocytic population was not while B-lymphocytic inhibited. Histological also LC-9018 markedly enhanced granulopoiesis marrow mice. same significantly increased 30-day survival rates athymic nude after lethal whole-body irradiation. blood by treatment. Our results suggest LC 9018 protected lethally from death enhancing rather than lymphopoiesis contribution activated T lymphocytes to enhancement small.
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