作者: Durairajan Rubini , Sanaulla Farisa Banu , B Narayanan Veda Hari , Durai Ramya Devi , Shanmugaraj Gowrishankar
DOI: 10.1016/J.FCT.2018.06.017
关键词: Microbiology 、 Staphyloxanthin 、 Staphylococcus aureus 、 Reactive oxygen species 、 Potency 、 Virulence 、 Chemistry 、 Methicillin-resistant Staphylococcus aureus 、 Chitosan 、 Biofilm
摘要: Multidrug-resistant (MDR) Staphylococcus aureus is a major cause of biofilm-associated and indwelling device related infections. The present study explores the anti-virulent and antibiofilm potency of chitosan extracted from the shells of the marine crab Portunus sanguinolentus against Methicillin Resistant Staphylococcus aureus (MRSA). The chemical characterization results revealed that the extracted chitosan (EC) has structural analogy to that of a commercial chitosan (CC). The extracted chitosan was found to be effective in …