Possible peripheral adrenergic and cholinergic mechanisms in pseudoconditioning.

摘要: Buzzers and shocks were presented in random sequence with no temporal association to rats a shuttle-box, so that they performed pseudoconditioned barrier-crossing responses the buzzer. Performance of these was enhanced by amphetamine tyramine. The adrenergic blocking agents yohimbine dibenamine, though ineffective on their own, antagonized action Hexamethonium methylatropine, also themselves, potentiated effect but not Eserine depressed performance when given alone, it stimulant both results suggest tyramine enhance pseudoconditioning through activation peripheral mechanism amphetamine, addition, triggers an opposing cholinergic mechanism, peripheral, from which can be released anticholinergic hexamethonium methylatropine. depressant eserine explained mechanism.