作者: Pierre Faurie , Christiane Broussolle , Fabien Zoulim , Christian Trepo , Pascal Sève
DOI: 10.1097/MEG.0B013E32833834BC
关键词: Arthritis 、 Systemic disease 、 Retrospective cohort study 、 Internal medicine 、 Alpha interferon 、 Ribavirin 、 Hepatitis C 、 Medicine 、 Immunology 、 Population 、 Sarcoidosis
摘要: UNLABELLED BASIC: To describe the main characteristics and treatment of sarcoidosis in patients with chronic hepatitis C virus (HCV) infection. METHODS Retrospective cohort study HCV infection at our tertiary institution. RESULTS Eleven cases (eight women, three men) fulfilled criteria for sarcoidosis. Four belong to population 3194 (0.12%) seen department between 2001 2008. In five cases, was triggered by antiviral therapy (consisted interferon-alpha monotherapy one case combined ribavirin four cases) developed from 23 82 months after completion cases. For these patients, pulmonary adenopathies were found while two presented cutaneous involvement, had uveitis both arthritis extrapulmonary lymphadenopathies. Two received systemic corticosteroids a favourable outcome. treatment-naive disease, medullar superficial lymphadenopathy arthralgia. Three outcome all One an earlier history experienced benign relapse that resolved spontaneously. CONCLUSION Clinical manifestations may occur especially during or immunotherapy. experience, more frequent therapy, but concording literature, sarcoidosis, be used often less favourable.