Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
作者： Toshihiro Mineta , Samuel D. Rabkin , Takahito Yazaki , William D. Hunter , Robert L. Martuza
DOI: 10.1038/NM0995-938
关键词: Pathology 、 Oncolytic herpes virus 、 Immunity 、 Ganciclovir 、 Cancer research 、 Medicine 、 Herpes simplex virus 、 Molecular medicine 、 Transplantation 、 Stem cell 、 Oncolytic Virus Therapy
摘要: We have created a double mutant of the herpes simplex virus (HSV) type 1 (termed G207) with favourable properties for treating human malignant brain tumours: replication–…
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