Chapter 1 The utility of zebrafish as a model for toxicological research
作者： Michael J. Carvan , Tisha King Heiden , Henry Tomasiewicz
DOI: 10.1016/S1873-0140(05)80004-9
关键词: Computational biology 、 Biology 、 Model system 、 Comparative biology 、 Zebrafish 、 Genetic model 、 Zoology 、 Model organism 、 Danio 、 Human disease
摘要: Publisher Summary This chapter explains the utility of zebrafish as a model for toxicological research. Zebrafish ( Danio rerio ) have long been genetic choice vertebrate developmental biologists, it provides several advantages investigating organ and tissue development. become powerful organism molecular cellular mechanisms by which environmental chemicals disrupt normal processes. The laboratory also makes an excellent system studying processes in juvenile adult organisms, including reproductive development, carcinogenesis, aging, influence on these advent modern tools genome sequencing projects has elevated suitable to effectively study human disease pathophysiology, ushering new era comparative biology medicine. reviews mechanistic toxicology system.
elsevier.com
sci-hub.se 参考文章(247)
Patrick Blader, Uwe Strähle, Casting an eye over cyclopia Nature. ,vol. 395, pp. 112- 113 ,(1998) , 10.1038/25836
Roland Nagel, DarT: The embryo test with the Zebrafish Danio rerio--a general model in ecotoxicology and toxicology. ALTEX-Alternatives to Animal Experimentation. pp. 38- 48 ,(2002)
Peter Matthiessen, John P. Sumpter, Effects of estrogenic substances in the aquatic environment EXS. ,vol. 86, pp. 319- 335 ,(1998) , 10.1007/978-3-0348-8853-0_10
John P. Sumpter, Reproductive Effects from Oestrogen Activity in Polluted Water Archives of Toxicology. ,vol. 20, pp. 143- 150 ,(1998) , 10.1007/978-3-642-46856-8_13
M Mizell, E S Romig, THE AQUATIC VERTEBRATE EMBRYO AS A SENTINEL FOR TOXINS : ZEBRAFISH EMBRYO DECHORIONATION AND PERIVITELLINE SPACE MICROINJECTION The International Journal of Developmental Biology. ,vol. 41, pp. 411- 423 ,(1997) , 10.1387/IJDB.9184351
Jurgen H. Exner, Perspective on Hazardous Waste Problems Related to Dioxins American Chemical Society. pp. 1- 17 ,(1987) , 10.1021/BK-1987-0338.CH001
Korach Ks, Couse Jf, Migliaccio S, Lubahn Db, Washburn Tf, Eddy Em, Curtis Sw, Schomberg Dw, Snedeker Sm, Lindzey J, Kimbro Ks, Smith Ep, Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes. Recent Progress in Hormone Research. ,vol. 51, pp. 159- ,(1996)
Robert Geisler, Gerd-Jörg Rauch, Herwig Baier, Frauke van Bebber, Linda Broβ, Marcus P.S. Dekens, Karin Finger, Cornelia Fricke, Michael A. Gates, Horst Geiger, Silke Geiger-Rudolph, Darren Gilmour, Stefanie Glaser, Lara Gnügge, Hinrich Habeck, Katy Hingst, Scott Holley, Jeremy Keenan, Anette Kirn, Holger Knaut, Deval Lashkari, Florian Maderspacher, Ulrike Martyn, Stephan Neuhauss, Carl Neumann, Teresa Nicolson, Francisco Pelegri, Russell Ray, Jens M. Rick, Henry Roehl, Tobias Roeser, Heike E. Schauerte, Alexander F. Schier, Ulrike Schönberger, Helia-Berrit Schönthaler, Stefan Schulte-Merker, Catrin Seydler, William S. Talbot, Christian Weiler, Christiane Nüsslein-Volhard, Pascal Haffter, A radiation hybrid map of the zebrafish genome Nature Genetics. ,vol. 23, pp. 86- 89 ,(1999) , 10.1038/12692
Kenichi Kenneth Hisaoka, The Effects of 2-Acetylaminofluorene on the Embryonic Development of the Zebrafish II. Histochemical Studies Cancer Research. ,vol. 18, pp. 664- 667 ,(1958)
Hans W. Laale, The biology and use of zebrafish, Brachydanio rerio in fisheries research. Journal of Fish Biology. ,vol. 10, pp. 121- 173 ,(1977) , 10.1111/J.1095-8649.1977.TB04049.X