作者: Nguyen V Cuong , Pawin Padungtod , Guy Thwaites , Juan J Carrique-Mas
DOI: 10.3390/ANTIBIOTICS7030075
关键词: Environmental health 、 Antimicrobial 、 Medicine 、 Web of knowledge 、 Livestock 、 Dairy cattle 、 Low and middle income countries 、 Food animal 、 Animal production 、 Antimicrobial use
摘要: Antimicrobial use (AMU) in animal production is a key contributor to antimicrobial resistance (AMR) worldwide. As consumption of protein and associated forecast increase markedly over coming years low- middle-income countries (LMICs), accurate monitoring AMU has become imperative. We summarized data from 89 scientific studies reporting published English since 1998, identified through the ‘ISI Web Knowledge’ search engine. The aims were as follows: (a) describe methodologies metrics used quantify AMU; (b) summarize qualitative (on-farm prevalence use) quantitative (amounts active principle) data, order identify food species at highest risk (c) highlight gaps LMICs. Only 17/89 (19.1%) conducted Sixty (67.3%) reported use, with ‘daily doses per animal-time’ being most common metric. was greatest chickens (138 doses/1000 animal-days [inter quartile range (IQR) 91.1–438.3]), followed by swine (40.2 [IQR 8.5–120.4]), dairy cattle (10.0 5.5–13.6]). However, kg meat produced, swine, cattle. Our review highlights large deficit LMICs, provides reference for comparison further surveillance research initiatives aiming reduce globally.