Latent M. tuberculosis infection--pathogenesis, diagnosis, treatment and prevention strategies

作者: MAGDALENA DRUSZCZYŃSKA , MAGDALENA KOWALEWICZ-KULBAT , MAREK FOL , MARCIN WŁODARCZYK , WIESŁAWA RUDNICKA

DOI: 10.33073/PJM-2012-001

关键词: Active tuberculosisMycobacterium tuberculosisActive tbTuberculosisDiagnosis treatmentPopulationPathogenesisMedicineImmunologyCancer

摘要: A b s t r a c One third of the earth ’ population is infected with Mycobacterium tuberculosis (Mtb ), but only 5–10% individuals develop active (TB) over their lifetime. "e remaining 90–95% stay healthy and are called latently individuals. "ey biggest reservoir tubercle bacilli identifying cases latent TB part global plan control. From clinical point view detection infections (LTBI) in highest risk including HIV infection, autoimmune in:ammatory diseases or cancer, priority. "is review summarizes recent findings pathogenesis TB, its diagnosis, treatment prevention.

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