Experimental Model to Evaluate Mechanical Closure Resistance of Sutureless Vitrectomy Sclerotomies Using Pig Eyes

摘要: PURPOSE. The purpose of this study was to report a novel model for comparing mechanical resistance intraocular pressure (IOP) increases with 23-gauge (23G) and 25G transconjunctival sutureless vitrectomy (TSV) sclerotomies in the immediate postoperative period using an experimental vitrectomized eye. METHODS. This prospective, experimental, randomized, observer-masked which TSV 23G oblique sclerotomies, performed same cadaveric pig eye, were subject increase IOP. Mechanical determined by fluid leak through sclerotomy. simultaneous use different sclerotomy diameters eye avoided interindividual scleral differences. RESULTS. animal allowed comparison effect (23G 25G) on incisional resistance. One hundred twenty eyes included. In 60.7% cases, first escape (leaked; P 0.02). When opening values, leaked at significantly lower levels than (P 0.0001); 53% incisions but only 16% opened greater 120 mm Hg. CONCLUSIONS. Oblique offer less IOP do sclerotomies. may become basis future studies evaluate advantages other types incision or surgical tools closure capacity. (Invest Ophthalmol Vis Sci. 2011;52:4080‐4084) DOI:10.1167/ iovs.10-6812