Computer-Aided Evaluation of Protein Expression in Pathological Tissue Images
作者： Elisa Ficarra , Enrico Macii , Giovanni De Micheli , Luca Benini
DOI: 10.1109/CBMS.2006.71
关键词: Computer-aided 、 Protein expression 、 Computer science 、 Artificial intelligence 、 Cellular biophysics 、 Pattern recognition 、 Medical imaging 、 Pathology
摘要: This work presents the first fully-automated computer-aided analysis approach to quantification of expression receptors for non-small cell lung carcinoma. immunohistochemical is usually performed by pathologists via visual inspection tissue samples images. Our techniques streamlines this error-prone and time-consuming process, thereby facilitating diagnosis. Experimental results on several real-life datasets demonstrate high quantitative precision our
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ieeecomputersociety.org参考文章(12)
T. W. Ridler, S. Calvard, Picture thresholding using an iterative selection method. IEEE Transactions on Systems, Man, and Cybernetics. ,vol. 8, pp. 630- 632 ,(1978)
Abderrahim Elmoataz, Sophie Schüpp, Régis Clouard, Paulette Herlin, Daniel Bloyet, Using active contours and mathematical morphology tools for quantification of immunohistochemical images Signal Processing. ,vol. 71, pp. 215- 226 ,(1998) , 10.1016/S0165-1684(98)00146-7
J. Kittler, J. Illingworth, Minimum error thresholding Pattern Recognition. ,vol. 19, pp. 41- 47 ,(1986) , 10.1016/0031-3203(86)90030-0
Norberto Malpica, Carlos Ortiz de Solórzano, Juan José Vaquero, Andrés Santos, Isabel Vallcorba, José Miguel García-Sagredo, Francisco del Pozo, APPLYING WATERSHED ALGORITHMS TO THE SEGMENTATION OF CLUSTERED NUCLEI Cytometry. ,vol. 28, pp. 289- 297 ,(1998) , 10.1002/(SICI)1097-0320(19970801)28:4<289::AID-CYTO3>3.0.CO;2-7
Arnout C. Ruifrok, Ruth L. Katz, Dennis A. Johnston, Comparison of quantification of histochemical staining by hue-saturation-intensity (HSI) transformation and color-deconvolution Applied Immunohistochemistry & Molecular Morphology. ,vol. 11, pp. 85- 91 ,(2003) , 10.1097/00129039-200303000-00014
M. Jacob, T. Blu, M. Unser, Efficient energies and algorithms for parametric snakes IEEE Transactions on Image Processing. ,vol. 13, pp. 1231- 1244 ,(2004) , 10.1109/TIP.2004.832919
Tarvinder Taneja, SK Sharma, Markers of small cell lung cancer World Journal of Surgical Oncology. ,vol. 2, pp. 10- 10 ,(2004) , 10.1186/1477-7819-2-10
Eric M. Brey, Zahid Lalani, Carol Johnston, Mark Wong, Larry V. McIntire, Pauline J. Duke, Charles W. Patrick, Automated Selection of DAB-labeled Tissue for Immunohistochemical Quantification Journal of Histochemistry and Cytochemistry. ,vol. 51, pp. 575- 584 ,(2003) , 10.1177/002215540305100503
Nobuyuki Otsu, A Threshold Selection Method from Gray-Level Histograms IEEE Transactions on Systems, Man, and Cybernetics. ,vol. 9, pp. 62- 66 ,(1979) , 10.1109/TSMC.1979.4310076
E. Ficarra, L. Benini, E. Macii, G. Zuccheri, Automated DNA fragments recognition and sizing through AFM image processing international conference of the ieee engineering in medicine and biology society. ,vol. 9, pp. 508- 517 ,(2005) , 10.1109/TITB.2005.855546