Long-term fish consumption is associated with protection against arrhythmia in healthy persons in a Mediterranean region—the ATTICA study

摘要: BACKGROUND:Dietary habits have long been associated with many manifestations of cardiovascular disease. OBJECTIVE:We sought to investigate whether a diet enriched fish and n-3 fatty acid consumption are changes in the potential duration electrical action, as represented by QT on resting electrocardiogram, population-based sample Greek adults. DESIGN:During 2001 2002, we randomly enrolled 1514 men (18-87 y old) 1528 women (18-89 stratified age sex distribution (in census) from Attica area, Greece. We studied several demographic, anthropometric, lifestyle, dietary, bioclinical factors participants. Dietary (including consumption) were evaluated using validated food-frequency questionnaire. All subjects underwent electrocardiography 12-lead surface, which, along other indexes, was measured, heart rate-corrected (QTc) calculated (corrected Bazett's rate). The tested hypothesis through multiple linear regression analysis, after control for physical activity status, sex, age, medication intake, confounders. RESULTS:Compared nonconsumers, those who consumed >300 g fish/wk had mean 13.6% lower QTc (P =300 29.2% likelihood having intervals >0.45 s = 0.03). CONCLUSIONS:Long-term is interval free-eating people without any evidence Thus, intake seems provide antiarrhythmic protection at population level.