Integrated global profiling of cancer.
作者： Samir Hanash
DOI: 10.1038/NRC1414
关键词: Computational biology 、 Genome 、 Genomics 、 Biology 、 Bioinformatics 、 Profiling (information science) 、 Host factors 、 Proteomics 、 Single type
摘要: Tumours are complex biological systems. No single type of molecular approach fully elucidates tumour behaviour, necessitating analysis at multiple levels encompassing genomics and proteomics. Integrated data sets required to determine the contributions genome alterations, host factors environmental exposures growth progression, as well consequences interactions between malignant or premalignant cells their microenvironment. The sheer amount heterogeneous nature that need be collected integrated daunting, but effort has already begun address these obstacles.
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