The High Prevalence of Vitamin D Insufficiency across Australian Populations Is Only Partly Explained by Season and Latitude

摘要: BACKGROUND: Inadequate sun exposure and dietary vitamin D intake can result in insufficiency. However, limited data are available on actual status predictors healthy individuals different regions by season. METHODS: We compared [25-hydroxyvitamin D; 25(OH)D] people < 60 years of age using from cross-sectional studies three across Australia: southeast Queensland (27°S; 167 females 211 males), Geelong region (38°S; 561 females), Tasmania (43°S; 432 298 males). RESULTS: The prevalence insufficiency (≤ 50 nmol/L) women winter/spring was 40.5% Queensland, 37.4% the region, 67.3% Tasmania. Season, simulated maximum daily duration synthesis, effective dose each explained around 14% variation 25(OH)D. Although latitude only 3.9% variation, a decrease average 25(OH)D 1.0 (95% confidence interval, 0.7‐1.3) nmol/L for every degree increase may be clinically relevant. In some months, we found high or even deficiency when protection would recommended basis ultraviolet index. CONCLUSION: Vitamin is common over wide range Australia. Season appears to more important than latitude, but both accounted less one-fifth serum levels, highlighting importance behavioral factors. Current guidelines do not seem fully prevent insufficiency, consideration should