The Effect of Cytochrome P-450-Dependent Metabolism and Other Enzyme Activities on Olfaction

摘要: The scientific fields of inhalation toxicology, foreign compound metabolism, and olfactory physiology share broad interests in the interaction materials with biological systems. Inhalation toxicologists physiologists a narrower common interest effects compounds on nasal tissues. are interested toxic effects, concern themselves stimulation to produce an response. third field be included here, that concerned has until recently been little (and largely confined metabolism inhaled lung liver) even less physiologists. But, increasing frequency which cancers other lesions have reported laboratory animals exposed toxicants by led increased research into response tissue materials. One recent finding is tissues high concentrations enzymes metabolize xenobiotics (Dahl, 1985a-c).