Histologic tumor regression grades in squamous cell carcinoma of the head and neck after preoperative radiochemotherapy.
作者： O. M. Braun , B. Neumeister , W. Popp , R. Scherrer , E. Dobrowsky
DOI: 10.1002/1097-0142(19890315)63:6<1097::AID-CNCR2820630610>3.0.CO;2-6
关键词: Surgery 、 Mitomycin C 、 Radiation therapy 、 Radiology 、 Tumor Regression Grade 、 Head and neck 、 Medicine 、 Concomitant 、 Chemotherapy 、 Tumor regression 、 Stage (cooking)
摘要: Forty-one patients with Stage III and IV squamous cell carcinomas (SCC) of the head neck were treated preoperatively mitomycin C 5-fluorouracil concomitant radiotherapy. Operation specimen examined histologically, percentage vital tumor cells devitalized graduated. The grade regression was classified according to a four-stage scale. Tumor elevated as good (Grades 1, 2) bad (3, 4) response combined preoperative therapy. After follow-up 18 30 months, 14 41 have experienced locoregional recurrence; all these responders 3, radiochemotherapy. There statistically significant correlation between probability survival (P less than 0.001). authors conclude that prognosis pretreated SCC depends on histologic regression.
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