Phospholipid electrospun nanofibers: effect of solvents and co-axial processing on morphology and fiber diameter

摘要: Asolectin phospholipid nano-microfibers were prepared using electrospinning processing. The asolectin fibers studied by scanning electron microscopy, and the fiber morphology was found to be strongly dependent on concentration solvents used. chloroform : dimethylformamide (CHCl3 : DMF, 3 : 2 v/v), isooctane, cyclohexane limonene, producing with average diameters in range of 2.57 ± 0.59 μm, ∼3–8 ∼4–5 μm 14.3 2.7 respectively. diameter electrospun does not follow theoretically predicted value ∼0.35 because intermolecular aggregation between reverse micelles formed highly concentrated solutions. However, when co-axial solvent applied, where outer needle contains a pure inner solution CHCl3:DMF, substantial reduction observed. In particular, DMF (a high dielectric constant) used as sheath reduced factor about 7 at nano-size range, predicted. constant had strong influence jet split properties affected fibers.