NBD-based fluorescent chemosensor for the selective quantification of copper and sulfide in an aqueous solution and living cells

摘要: Chemosensors play important roles in cation and anion recognition biological, industrial, environmental processes. Although many efforts have been made to develop artificial fluorescent receptors for Cu2+ S2−, their applications the detection bulk solutions are limited. In this work, we report a novel fluorescence chemosensor (NL) based on 7-nitrobenz-2-oxa-1,3-diazole (NBD) fluorophore quantification of S2− single intact cells. NL specifically binds presence other competing cations, evident changes UV-vis spectra HEPES buffer noticed. Based displacement approach, selective sense with situ generated NL-Cu2+ ensemble gives remarkable recovery absorption spectra. The limits were estimated be 1.6 nM 0.17 μM, respectively. resultant complex exhibit low cytotoxicity cell-membrane permeability, which makes them capable imaging living MDA-MB-231