Melanocytic bronchial carcinoid tumor
作者： Marilyn S. Cebelin
DOI: 10.1002/1097-0142(19801015)46:8<1843::AID-CNCR2820460823>3.0.CO;2-C
关键词: APUD cell 、 Cell 、 BRONCHIAL CARCINOID TUMOR 、 Melanin synthesis 、 Pathology 、 Serotonin 、 Endocrine system 、 Biology 、 Melanin 、 Assay 、 Cancer research 、 Oncology
摘要: A melanin- and serotonin-producing bronchial carcinoid tumor is described. Melanin synthesis by neoplastic cells also containing electron-dense core (neurosecretory granules was documented electron microscopy serotonin content found biochemical assay to be 201.2 micrograms/g wet weight of tissue. Simultaneous demonstration "endocrine" properties with characteristics a cell neural-crest origin provides strongly confirmatory evidence for the APUD theory Pearse makes an interesting commentary in regard general theories neoplasia.
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