CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma

作者: J Chu , Y Deng , D M Benson , S He , T Hughes

DOI: 10.1038/LEU.2013.279

关键词: Janus kinase 3Lymphokine-activated killer cellCancer researchBiologyInterleukin 21Immune systemInterleukin 12CD40Adoptive cell transferNatural killer T cellImmunology

摘要: … of T cells or NK cells with chimeric antigen receptors (CARs) that directly target tumor-associated antigens. In fact, CAR T … All animal work was approved by The Ohio State University …

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