作者: Natalia Prodan , Markus Hoopmann , Jiri Sonek , Christoph Oettling , Harald Abele
DOI: 10.1007/S00404-020-05503-8
关键词: Spina bifida 、 Gestation 、 Pregnancy 、 Medicine 、 Normal values 、 Obstetrics 、 Screening programs 、 Open spina bifida 、 Fetus 、 Ultrasound
摘要: To determine whether the frontomaxillary facial (FMF) angle and prefrontal space ratio (PFSR) are helpful in screening for open spinal defects by ultrasound second third trimesters of pregnancy. The FMF PFSR were measured fetuses with spina bifida according to standardized protocols. normal range was previously published our group. values pregnancy, we used same stored images from above-mentioned study. 71 affected 279 included this Median gestational ages two groups 21.1 weeks 21.6 weeks, respectively. In bifida, significantly smaller than population (72.9° versus 79.6°). However, measurement below fifth centile only 22.5% fetuses. similar both groups. is trimester bifida. difference not large enough implement marker current programs.