Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt
作者： Justin E Wilson , Alex S Petrucelli , Liang Chen , A Alicia Koblansky , Agnieszka D Truax
DOI: 10.1038/NM.3908
关键词: Protein kinase B 、 Colorectal cancer 、 Protein kinase A 、 Phosphorylation 、 Cancer research 、 Biology 、 Azoxymethane 、 AIM2 、 Cancer 、 Inflammasome
摘要: The inflammasome activates caspase-1 and the release of interleukin-1β (IL-1β) and IL-18, and several inflammasomes protect against intestinal inflammation and colitis-associated …
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