Mutant human prourokinase
作者： Yasuo Amatsuji , Masaaki Hirose , Masanori Morita , Toshizumi Tanabe
DOI:
关键词: Plasmid 、 Amino acid 、 Mutant 、 Fibrin 、 Molecular biology 、 Biology 、 Biochemistry 、 Fibrinolysin 、 Epidermal growth factor
摘要: A mutant human prourokinase wherein a neutral amino acid in the epidermal growth factor (EGF) region of (human PUK) has been replaced with basic acid, or an acidic non-acidic and method for producing PUK which comprises expression by cultivating host transformed plasmid inserted DNA sequence coding said PUK. By replacing EGF is fibrinolysin half-life blood can be prolonged, affinity fibrin improved.
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