Motoric cognitive risk syndrome and risk of mortality in older adults
作者： Emmeline Ayers , Joe Verghese
DOI: 10.1016/J.JALZ.2015.08.167
关键词: Logistic regression 、 Gerontology 、 Odds ratio 、 Confidence interval 、 Cognition 、 Hazard ratio 、 Cohort study 、 Psychology 、 Dementia 、 Internal medicine 、 Risk of mortality
摘要: Abstract Introduction Cognitive impairment is associated with increased mortality. We examined the association between motoric cognitive risk (MCR) syndrome, a predementia syndrome characterized by slow gait and complaints, survival. Methods A total of 11,867 nondemented participants aged >65 years from three established cohort studies in United States Europe were screened for MCR. Mortality MCR was assessed Cox logistic regression models. Results At baseline, 836 (7.0%) had Over median follow-up 28 months, 1603 died (758 first 2 years). mortality overall (adjusted hazard ratio, 1.69; 95% confidence interval [CI], 1.46–1.96) 2-year odds 1.89; CI, 1.50–2.38). The remained after accounting factors as well baseline speed memory performance. Discussion Older adults should be to identify at-risk individuals dementia death.
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