Overexpression of Matrix Metalloproteinase-21 is Associated with Poor Overall Survival of Patients with Colorectal Cancer

作者: Yi Huang , Wenhai Li , Dake Chu , Jianyong Zheng , Gang Ji

DOI: 10.1007/S11605-011-1519-5

关键词: Matrix metalloproteinaseColorectal tissueMedicineTissue microarrayMetastasisOncologyColorectal cancerOverall survivalMatrix (biology)Internal medicineSurgeryGastroenterology

摘要: Introduction Matrix metalloproteinase-21 (MMP-21) is a member of the MMP family, which overexpressed in some solid tumors and thought to enhance tumor invasion metastasis ability. The aim present study examine MMP-21 expression human colorectal cancer normal tissue using microarray technique determine its association with clinicopathological characteristics prognostic value.

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