Using the Molecular Classification of Glioblastoma to Inform Personalized Treatment

作者: Adriana Olar , Kenneth D Aldape

DOI: 10.1002/PATH.4282

关键词: Diffuse GliomaMolecular classificationBiologyDiseaseGlioblastomaPathophysiologyDrug developmentBioinformaticsPersonalized treatmentPrecision medicine

摘要: … As shown by our group 9, the absence of IDH1–R132H … Antibody-negative gliomas are interrogated at IDH1 132 and … tyrosine kinase inhibitors (erlotinib, gefitinib) in newly diagnosed or …

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