Water proton MR properties of human blood at 1.5 Tesla: Magnetic susceptibility, T1, T2, T *2, and non‐Lorentzian signal behavior

摘要: Accurate knowledge of the magnetic properties human blood is required for precise modeling functional and vascular flow-related MRI. Herein are reported determinations relaxation parameters blood, employing in vitro samples that well representative situ. The envelope (1)H(2)O free-induction decay signal magnitude during first 100 msec following a spin echo at time TE well- described empirically by an expression form, S(t) = S(o). exp[-R(*)(2). (t - TE) AR*. TE)(2)]. AR* R(*)(2) increase as function square susceptibility difference between red cell plasma depend on spin-echo time. Gaussian component, AR*, should be recognized accurate MRI phenomena upon state blood. fully deoxygenated oxygenated cells 37 degrees C 0.27 ppm, determined independently MR superconducting quantum interference device (SQUID) measurements. This value agrees with 1936 report Pauling Coryell (Proc Natl Acad Sci USA 1936;22:210-216), but substantially larger than frequently used literature. Magn Reson Med 45:533-542, 2001.