The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification
作者： Frédéric Gachon , Fabienne Fleury Olela , Olivier Schaad , Patrick Descombes , Ueli Schibler
DOI: 10.1016/J.CMET.2006.04.015
关键词: Knockout mouse 、 Hepatic Leukemia Factor 、 Cell biology 、 Cytochrome P450 、 Transcription factor 、 Biochemistry 、 Mutant 、 Transcriptome 、 Constitutive androstane receptor 、 Biology 、 Gene
摘要: … and drug metabolism, such as cytochrome P450 enzymes, … Based on a simple mathematical simulation of circadian mRNA … A DNA microarray search for transcripts whose accumulation …
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