Regulation of ATG8 membrane association by ATG4 in the parasitic protist Toxoplasma gondii

作者: Marie A. Kong-Hap , Annabelle Mouammine , Wassim Daher , Laurence Berry , Maryse Lebrun

DOI: 10.4161/AUTO.25189

关键词: BiochemistryToxoplasma gondiiApicoplastATG8AutophagyOrganelleBiologyCell biologyPlastidCytosolMitochondrion

摘要: … by the cysteine peptidase Atg4 to expose the specific glycine … as it is being generated, Atg4 also appears to be able to … Atg4-dependent cleavage of Atg8–PE, but both this and Atg4-…

参考文章(46)
Zhifen Yang, Daniel J. Klionsky, An Overview of the Molecular Mechanism of Autophagy Current Topics in Microbiology and Immunology. ,vol. 335, pp. 1- 32 ,(2009) , 10.1007/978-3-642-00302-8_1
Manel Camps, Gustavo Arrizabalaga, John Boothroyd, An rRNA mutation identifies the apicoplast as the target for clindamycin in Toxoplasma gondii. Molecular Microbiology. ,vol. 43, pp. 1309- 1318 ,(2002) , 10.1046/J.1365-2958.2002.02825.X
Hitoshi Nakatogawa, Yoshinobu Ichimura, Yoshinori Ohsumi, Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion Cell. ,vol. 130, pp. 165- 178 ,(2007) , 10.1016/J.CELL.2007.05.021
Sébastien Besteiro, Justine Bertrand-Michel, Maryse Lebrun, Henri Vial, Jean-François Dubremetz, Lipidomic analysis of Toxoplasma gondii tachyzoites rhoptries: further insights into the role of cholesterol. Biochemical Journal. ,vol. 415, pp. 87- 96 ,(2008) , 10.1042/BJ20080795
Marc-Jan Gubbels, Margaret Lehmann, Mani Muthalagi, Maria E Jerome, Carrie F Brooks, Tomasz Szatanek, Jayme Flynn, Ben Parrot, Josh Radke, Boris Striepen, Michael W White, Forward Genetic Analysis of the Apicomplexan Cell Division Cycle in Toxoplasma gondii PLOS Pathogens. ,vol. 4, ,(2008) , 10.1371/JOURNAL.PPAT.0040036
Usha Nair, Wei-Lien Yen, Muriel Mari, Yang Cao, Zhiping Xie, Misuzu Baba, Fulvio Reggiori, Daniel J Klionsky, A role for Atg8–PE deconjugation in autophagosome biogenesis Autophagy. ,vol. 8, pp. 780- 793 ,(2012) , 10.4161/AUTO.19385
Philippe Bastin, Azadeh Bagherzadeh, Keith R. Matthews, Keith Gull, A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei. Molecular and Biochemical Parasitology. ,vol. 77, pp. 235- 239 ,(1996) , 10.1016/0166-6851(96)02598-4
Nathalie Garcia-Reguet, Maryse Lebrun, Marie-Noelle Fourmaux, Odile Mercereau-Puijalon, Tara Mann, Cornelius J. M. Beckers, Bart Samyn, Jozef Van Beeumen, Daniel Bout, Jean-Francois Dubremetz, The microneme protein MIC3 of Toxoplasma gondii is a secretory adhesin that binds to both the surface of the host cells and the surface of the parasite Cellular Microbiology. ,vol. 2, pp. 353- 364 ,(2000) , 10.1046/J.1462-5822.2000.00064.X
David C. Rubinsztein, Patrice Codogno, Beth Levine, Autophagy modulation as a potential therapeutic target for diverse diseases Nature Reviews Drug Discovery. ,vol. 11, pp. 709- 730 ,(2012) , 10.1038/NRD3802