Autophagy-inducing peptide
作者： Sanae Shoji-Kawata , Olivier Lichtarge , Angela D. Wilkins , Beth C. Levine
DOI:
关键词: Biology 、 Heterologous 、 Moiety 、 Peptide 、 Autophagy 、 Biochemistry
摘要: An autophagy-inducing compound comprises an peptide comprising beclin-1 residues 269-283 and a heterologous moiety that promotes therapeutic stability or delivery of the compound. The may be used to induce autophagy in assays with binding partners.
lens.org 参考文章(6)
Jianrong Wang, Beclin 1 bridges autophagy, apoptosis and differentiation Autophagy. ,vol. 4, pp. 947- 948 ,(2008) , 10.4161/AUTO.6787
Sabrina Di Bartolomeo, Marco Corazzari, Francesca Nazio, Serafina Oliverio, Gaia Lisi, Manuela Antonioli, Vittoria Pagliarini, Silvia Matteoni, Claudia Fuoco, Luigi Giunta, Marcello D'Amelio, Roberta Nardacci, Alessandra Romagnoli, Mauro Piacentini, Francesco Cecconi, Gian Maria Fimia, The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy Journal of Cell Biology. ,vol. 191, pp. 155- 168 ,(2010) , 10.1083/JCB.201002100
R Kang, H J Zeh, M T Lotze, D Tang, The Beclin 1 network regulates autophagy and apoptosis Cell Death & Differentiation. ,vol. 18, pp. 571- 580 ,(2011) , 10.1038/CDD.2010.191
Qiming Sun, Weiliang Fan, Qing Zhong, Regulation of Beclin 1 in autophagy Autophagy. ,vol. 5, pp. 713- 716 ,(2009) , 10.4161/AUTO.5.5.8524
Eric H. Baehrecke, Yu Li, Michael J. Lenardo, Ajjai Alva, Function of autophagy genes in cell death ,(2005)
Roberta A. Gottlieb, Compositions and methods for modulating autophagy ,(2011)