Noninvasive assessment of left atrial function by strain rate imaging in patients with hypertension: a possible beneficial effect of renin-angiotensin system inhibition on left atrial function.

摘要: Renin-angiotensin system (RAS) inhibitors are likely to reduce the development of atrial fibrillation by preventing fibrosis. Strain rate (SR) imaging is a novel echocardiographic technique quantify left (LA) function. However, it has not been determined whether SR applicable for detection LA dysfunction in hypertensive (HT) patients. We used assess alteration function HT patients and its modification RAS inhibitors. was performed 80 50 age-matched normotensive (NT) subjects. were divided into two groups according ventricular hypertrophy (LVH) dilatation. Peak measured at each segment (septal, lateral, posterior, anterior, inferior) mean peak systolic (SR-LAs) calculated averaging data segment. Mean SR-LAs levels dilated group (1.97+/-0.45 s(-1), n=25) non-dilated (2.15+/-0.57 n=55) significantly (p<0.05) lower than that NT subjects (2.53+/-0.71 s(-1)). Irrespective presence or absence LVH, When used, level equivalent In patients, SR-LAs, an index reservoir function, decreases before enlargement LVH. Treatment with appears preserve without LA. can detect useful evaluation therapeutic benefit on