Genetic characterization of the unique short segment of Phocid herpesvirus type 1 reveals close relationships among alphaherpesviruses of hosts of the order Carnivora
作者： B. E. E. Martina , T. C. Harder , A. D. M. E. Osterhaus
关键词: Herpes simplex virus 、 Biology 、 Phylogenetics 、 Equivalent 、 Gene 、 Virology 、 Open reading frame 、 ORFS 、 Glycoprotein 、 Genetics 、 Canine herpesvirus
摘要: To further characterize phocid herpesvirus type 1 (PhHV-1) at the molecular level, a cluster of genes comprising complete unique short (Us) region PhHV-1 has been cloned and sequenced. Within this region, ORFs were detected that code for equivalent Us 2− protein herpes simplex virus (HSV), putative kinase, glycoprotein equivalents gG, gD, gI gE. In addition, two small downstream gE, homologous to 8·5 9 proteins HSV identified. Comparative analysis ORF encoding gD identified corresponding alphaherpesviruses canine and, lesser degree, feline as closest relatives.
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