Methods of using deacetylase inhibitors to promote cell differentiation and regeneration

摘要: A method of enhancing progenitor cell differentiation, including myogenesis, neurogenesis, and hematopoiesis, by contacting a with an effective amount deacetylase inhibitor (DI). The can be part culture, such as culture used for in vitro or vivo analysis organsism, human other mammal. Contacting the DI lead to enhancement expression terminal cell-type specific genes cell, muscle-specific myoblasts. Administering subject also provide some prophylactic therapeutic effect inhibiting, preventing, treating associated degeneration loss tissue. administered pharmaceutical composition.