Pigs, Poultry, and Pandemic Influenza: How Zoonotic Pathogens Threaten Human Health
作者： Thijs Kuiken , Ron Fouchier , Guus Rimmelzwaan , Judith van den Brand , Debby van Riel
DOI: 10.1007/978-1-4614-0204-6_6
关键词: Host (biology) 、 Transmission (medicine) 、 Pandemic influenza 、 Virology 、 Human health 、 Pandemic 、 Virus 、 Biology 、 Population 、 Influenza A virus subtype H5N1
摘要: Emerging infections have an enormous impact on human health, food supply, economics, and the environment. Animals, wild animals in particular, are considered to be source of more than 70% all emerging humans. Two zoonotic influenza viruses that successfully spread from humans highly pathogenic avian (HPAI) H5N1 virus, originating poultry, pandemic H1N1 (pH1N1) thought originate domestic swine. In this review, we discuss our research host species barrier for these viruses, concentrating three questions: how does HPAI virus transmit birds humans; what within-host dynamics pH1N1 other mammals; determines transmission among To contain eradicate requires not only strategic surveillance both animal populations, but also a better understanding hurdles such needs jump over order cross cause pandemic. Advances two areas will allow us predict risk emergence population.
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